Malignant potential in a Brunner's gland hamartoma.
نویسندگان
چکیده
Brunner's gland hamartomas are rare tumours of the duodenum. These lesions have previously been described as being benign, with no malignant potential. A case report is presented of a Brunner's gland hamartoma, whose histology revealed a focus of well marked epithelial dysplasia. This case suggests a dysplastic stage in the natural history of Brunner's gland hamartoma, and questions the malignant potential of these lesions.
منابع مشابه
Brunner's Gland Hamartoma: Is It Just a Morphologic Curiosity?
Brunner's gland hamartoma (BGH), characterized by benign proliferation of the Brunner's glands, was first described by Cruveilhier in 1835. Since then, case reports have been sporadic, and virtually all were clinicopathologic studies.2-13 Many patients with BGH were asymptomatic,13 while others presented with bleeding,3,6-8,12,13 duodenal obstruction, intussusception, or obstruction of the comm...
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Brunner's gland hamartoma, also called hyperplasia, adenoma, and Brunneroma, is an extremely rare benign proliferative lesion of Brunner's glands in the duodenum. While being mostly small and asymptomatic, they can result in gastrointestinal bleeding and obstruction. We report the case of a 54-year-old man presenting with melena and severe anemia requiring blood transfusion. CT scans showed a l...
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BACKGROUND Brunner's hamartoma is a quite rare neoformation whose origin is not completely clear. METHODS A case of a 69-year-old man with recurrent epigastric pain and an endoscopic finding of a duodenal mass is reported. RESULTS The complete removal of hamartoma can give a complete remission of symptoms. CONCLUSIONS Hamartoma can be only diagnosed by endoscopy and histological exam; its...
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Brunner's gland hamartomas are small benign lesions that are most commonly found in the bulb of the duodenum. They are very uncommon, and most are found incidentally during upper gastrointestinal series or esophagogastroduodenoscopy. The lesions tend to be asymptomatic, but patients may present with symptoms of duodenal obstruction or hemorrhage secondary to ulceration. Histologically, a Brunne...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 79 933 شماره
صفحات -
تاریخ انتشار 2003